
Pterosin B
CAS No. 34175-96-7
Pterosin B( 2R)-Pterosin B )
Catalog No. M14162 CAS No. 34175-96-7
Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 314 | In Stock |
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50MG | 1188 | In Stock |
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100MG | 1791 | In Stock |
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Biological Information
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Product NamePterosin B
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NoteResearch use only, not for human use.
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Brief DescriptionPterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.
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DescriptionPterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain; shows no effect on up-regulation of MEF2 and down-regulation of CRTC2 activities by SIK1 or SIK2; promotes glucose production by up-regulating gluconeogenic gene expression in mouse hepatoma AML-12 cells, decreases the glycogen content and stimulates an association between PHKG2 and SIK3.
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In Vitro——
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In Vivo——
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Synonyms2R)-Pterosin B
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PathwayAutophagy
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TargetSIK
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RecptorSIK
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number34175-96-7
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Formula Weight218.296
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Molecular FormulaC14H18O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1145.27 mM)
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SMILESCC1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C
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Chemical Name1H-Inden-1-one, 2,3-dihydro-6-(2-hydroxyethyl)-2,5,7-trimethyl-, (R)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Itoh Y, et al. J Biol Chem. 2015 Jul 17;290(29):17879-93.
2. Yahara Y, et al. Nat Commun. 2016 Mar 24;7:10959.
molnova catalog



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Pterosin B
Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.